| 摘要 |
Disclosed is a method for producing an optically active 2-arylpiperidinium salt, comprising asymmetrically hydrogenating a pyridinium salt in the presence of an iridium complex and hydrogen, the 2-arylpiperidinium salt being represented by the following general formula (1):
wherein R 1 , R 2 , X, *, and m are as described in Description, the pyridinium salt being represented by the following general formula (2):
wherein R 1 , R 2 , X, and m are as described in Description, and the iridium complex being represented by the following general formula (3):
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒIrH(Z)(Q)(PP*)€ƒ€ƒ€ƒ€ƒ€ƒ(3),
wherein Z, PP*, and Q are as described in Description, or the following general formula (4):
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ[{IrH(PP*)} 2 (µ-Z) 3 ]Z€ƒ€ƒ€ƒ€ƒ€ƒ(4),
wherein Z and PP* are as described in Description. |
