发明名称 |
HYDROCHLORIDE SALT OF ((1S,2S,4R)-4-{4-[(1S)-2,3-DIHYDRO-1H-INDEN-1-YLAMINO]-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL}-2-HYDROXYCYCLOPENTYL)METHYL SULFAMATE |
摘要 |
Disclosed is a compound of formula ( I ):
crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer. |
申请公布号 |
EP3091020(A3) |
申请公布日期 |
2017.01.11 |
申请号 |
EP20160159438 |
申请日期 |
2010.05.13 |
申请人 |
Millennium Pharmaceuticals, Inc. |
发明人 |
Armitage, Ian G;Chopra, Reenu;Cooper, Martin Ian;Langston, Marianne;Langston, Steven P.;Vyskocil, Stepan |
分类号 |
C07D487/04;A61K31/52;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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