发明名称 |
METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY |
摘要 |
A liquid composition suitable for topical use comprising is provided that includes a phospholipid foaming agent and at least one solvent; and a pharmaceutically acceptable active agent; wherein the liquid composition is capable of mechanically foaming without an additional propellant; and wherein upon mechanical foaming of 250 ml of the liquid composition results in a foam with a foam volume of at least about 400 ml and a foam stability wherein at least about 50% of the foam volume is still present after about 5 minutes at 25° C., as determined using a SITA foam measurement. Also provided herein are methods of making disclosed compositions and methods of use. |
申请公布号 |
EP2387391(B1) |
申请公布日期 |
2017.01.11 |
申请号 |
EP20100757384 |
申请日期 |
2010.07.16 |
申请人 |
MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH |
发明人 |
SEIGFRIED, Bernd, G. |
分类号 |
A61K9/12;A61K31/167;A61K31/192;A61K31/196;A61K31/4174;A61K31/573;A61K31/7048 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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