发明名称 インプラント用コーティング剤、インプラント及びインプラントの製造方法
摘要 PROBLEM TO BE SOLVED: To provide a coating agent for an implant capable of alleviating inflammations attributed to implant materials.SOLUTION: The provided coating agent for an implant is a coating agent for an implant comprising an artificial protein (A) wherein (A) includes a polypeptide chain (Y) formed by 2-200 continuous sequencing of at least one type of amino acid sequence (X) selected from among GVGVP sequence (1), PGVGV sequence (2), VPGVG sequence (3), GVPGV sequence (4), VGVPG sequence (5), and GPP sequence, GAP sequence, and GAHGPAGPK sequence (6) and/or the following polypeptide chain (Y'), wherein the total number of (Y) and (Y') within (A) is 1-100, and wherein the degree of hydrophobicity of (A) is 0.2-1.2. The polypeptide chain (Y') is a polypeptide chain in which 0.1-10%, in terms of number, of amino acids within (Y) have been substituted with lysine and/or arginine.
申请公布号 JP6058367(B2) 申请公布日期 2017.01.11
申请号 JP20120260053 申请日期 2012.11.28
申请人 三洋化成工業株式会社 发明人 杣本 聡
分类号 A61L27/22;A61L27/34;C07K7/00;C07K14/00 主分类号 A61L27/22
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