| 发明名称 | Methods for treating suicidal ideation | ||
| 摘要 | Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years). | ||
| 申请公布号 | US9539220(B2) | 申请公布日期 | 2017.01.10 |
| 申请号 | US201414197767 | 申请日期 | 2014.03.05 |
| 申请人 | Icahn School of Medicine at Mount Sinai;Yale University;The United States of America, as represented by The Secretary, Department of Health and Human Services | 发明人 | Charney Dennis S.;Mathew Sanjay J.;Manji Husseini K.;Zarate Carlos A.;Krystal John H. |
| 分类号 | A61K31/135;A61K31/137;A61K9/00;A61K9/70;A61K45/06;A61M15/08 | 主分类号 | A61K31/135 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A method of treating recurrent thoughts of death, suicidal ideation or suicidal attempts, consisting of intranasally administering to a patient who suffers from at least one of said recurrent thoughts of death, suicidal ideation or suicidal attempts a composition consisting of ketamine at a dosage sufficient to alleviate said recurrent thoughts of death, suicidal ideation or suicidal attempts and at least one pharmaceutically acceptable excipient. | ||
| 地址 | New York NY US | ||