| 发明名称 | Apparatus and methods for ocular injection | ||
| 摘要 | An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location. | ||
| 申请公布号 | US9539139(B2) | 申请公布日期 | 2017.01.10 |
| 申请号 | US201414268687 | 申请日期 | 2014.05.02 |
| 申请人 | Clearside Biomedical, Inc. | 发明人 | Andino Rafael Victor;Zarnitsyn Vladimir;Brooks Christopher John;Kahute Trent John;Arsenault Justin William;Trettin David Jackson;Bauer Andrew Kent;Lewis Stephanie Elaine |
| 分类号 | A61M5/00;A61F9/00;A61M5/31;A61M5/34;A61M5/46;A61M37/00;A61M5/20;A61M5/48;A61J1/20 | 主分类号 | A61M5/00 |
| 代理机构 | Cooley LLP | 代理人 | Cooley LLP |
| 主权项 | 1. An apparatus, comprising: a housing configured to receive a portion of a medicament container; a hub coupled to the housing, the hub defining a passageway configured to receive a puncture member therethrough, the hub having a convex distal end surface, the distal end surface of the hub configured to contact a target surface of a target tissue when a substance is conveyed through the puncture member; and an actuation rod at least partially disposed within the medicament container, the medicament container the actuation rod, and the puncture member collectively configured such that (1) a distal end portion of the actuation rod moves within the medicament container in response to a force on the actuation rod when a distal end portion of the puncture member is disposed within a first region of the target tissue, and (2) movement of the distal end portion of the actuation rod within the medicament container in response to the force on the actuation rod is limited when the distal end portion of the puncture member is disposed within a second region of the target tissue, the force having a magnitude less than a threshold value. | ||
| 地址 | Alpharetta GA US | ||