发明名称 |
NOVEL AMINO IMIDAZOLE COMPOUNDS SELECTIVELY SUPPRESS OXIDATIVE STRESS INDUCED NEURODEGENERATION |
摘要 |
An object of the present invention is to provide a pharmaceutical agent useful for treating and preventing neurological disease, having satisfactory solubility and oxidative stress-mediated cell death suppressive activity as well as capable of exhibiting excellent blood-brain barrier permeability. The present invention is directed to an acylaminoimidazole derivative represented by general formula (I) or a salt thereof, and a pharmaceutical and a therapeutic or preventive agent for neurological disease containing the same, as an active ingredient. (see formula I) |
申请公布号 |
CA2806766(C) |
申请公布日期 |
2017.01.10 |
申请号 |
CA20112806766 |
申请日期 |
2011.07.15 |
申请人 |
NEUGEN PHARMA INC.;WAKUNAGA PHARMACEUTICAL CO., LTD. |
发明人 |
INOUE, SATOSHI;IKEDA, JOH-E;HIRAYAMA, NORIAKI;TANAKA, KAZUNORI;KANNO, TAKUYA |
分类号 |
C07D233/88;A61K31/4168;A61K31/4439;A61P25/00;A61P25/02;A61P25/16;A61P25/28;A61P43/00;C07D401/04 |
主分类号 |
C07D233/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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