Defibrotide for use in prophylaxis and/or treatment of graft versus host disease (GVHD)

摘要

Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD) in humans is disclosed, preferably in hematopoietic stem cell transplantation (HSCT), more preferably allogeneic hematopoietic stem cell transplantation. Graft versus Host Disease of the invention (GVHD) can be acute aGVHD and/or chronic cGVHD, preferably acute.

主权项

1. A method of preventing or alleviating graft versus host disease (GVHD) comprising identifying a patient at risk of developing GVHD, and administering to the patient an amount of defibrotide sufficient to reduce the occurrence or severity of GVHD.