Treatment of circadian rhythm disorders

摘要

Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light perception impaired patients, e.g., blind patients, and to methods of measuring circadian rhythm.

主权项

1. A method of treating a patient for a circadian rhythm disorder wherein the patient is being treated with a strong CYP1A2 inhibitor selected from a group consisting of fluvoxamine, ciprofloxacin, and verapamil, the method comprising:
discontinuing the treatment with the strong CYP1A2 inhibitor; and then treating the patient with tasimelteion, thereby avoiding the use of tasimelteon in combination with the strong CYP1A2 inhibitor.