Method for amplifying abnormal pattern signal in observed brain activity of a subject for diagnosis or treatment

摘要

The present invention relates to a brain dysfunction and seizure detector monitor and system, and a method of detecting brain dysfunction and/or seizure of a subject. Preferably, the present invention also includes one or more seizure detection algorithms. The analysis method is specifically optimized to amplify abnormal brain activity and minimize normal background activity yielding a seizure index directly related to the current presence of ictal activity in the signal. Additionally, a seizure probability index based on historical values of the aforementioned seizure index, is derived for diagnostic purposes. The seizure probability index quantifies the probability that the patient has exhibited abnormal brain activity since the beginning of the recording. These indexes can be used in the context of emergency and/or clinical situations to assess the status and well-being of a patient's brain, or can be used to automatically administer treatment to stop the seizure before clinical signs appear.

主权项

1. A method for amplifying abnormal pattern signals in brainwaves or other brain related signals of a subject for diagnosis or treatment purposes comprising steps of:
acquiring at least one brain wave or other brain related signal with at least one sensor from a subject; applying a transform to the at least one brain wave or other brain related signal with a processor to obtain at least two coefficients from the at least one brain wave or other brain related signal; aligning those coefficients with electronics or the processor corresponding with at least one abnormal pattern signal; combining the aligned coefficients corresponding with the at least one abnormal pattern signal with electronics or the processor; outputting a signal or data corresponding to the aligned and combined coefficients to a monitor or a printer; using the outputted aligned and combined coefficients corresponding with the at least one abnormal pattern signal to identify the subject's abnormal pattern signal from the at least one brain wave or other brain related signal; and diagnosing and/or treating by a care provider or clinician, abnormal brain activity of the subject based at least in part on the identified abnormal pattern signal.