| 发明名称 | 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins | ||
| 摘要 | The present invention relates to substituted pyrrolopyridinones and substituted pyrazolopyridinones which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer. | ||
| 申请公布号 | US9540368(B2) | 申请公布日期 | 2017.01.10 |
| 申请号 | US201514693424 | 申请日期 | 2015.04.22 |
| 申请人 | Incyte Corporation | 发明人 | Combs Andrew P.;Maduskuie, Jr. Thomas P. |
| 分类号 | C07D471/04 | 主分类号 | C07D471/04 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A compound which is 2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-1,4-benzoxazin-3(4H)-one,-or a pharmaceutically acceptable salt thereof. | ||
| 地址 | Wilmington DE US | ||