发明名称 |
NOVEL DISUBSTITUTED 1,2, 4-TRIAZINE COMPOUND |
摘要 |
The present invention provides: a novel disubstituted 1, 2, 4-triazine compound that has an aldosterone synthase inhibitory activity and is useful in the prevention and/or treatment of various diseases or symptoms involving aldosterone, or a pharmaceutically acceptable salt of said compound; a method for producing same; a use for same; and a pharmaceutical composition, etc. formed using the compound or pharmaceutically acceptable salt thereof as an active ingredient. Provided is a compound represented by general formula [I]: [In the formula, RA is a group, etc. represented by formula (A-1) (in the formula, ring A1 is an optionally substituted cycloalkyl group, etc.), and RB is a monocyclic cycloalkyl group, etc.], or a pharmaceutically acceptable salt of said compound. |
申请公布号 |
PH12016502103(A1) |
申请公布日期 |
2017.01.09 |
申请号 |
PH2003120165021 |
申请日期 |
2016.10.20 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION |
发明人 |
USHIROGOCHI, HIDEKI;SASAKI, WATARU;ONDA, YUICHI;SAKAKIBARA, RYO;AKAHOSHI, FUMIHIKO |
分类号 |
A61K31/53;A61K31/5377;A61K31/541;A61K31/553;A61P1/16;A61P3/04;A61P3/12;A61P5/38;A61P5/42;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P13/12;A61P25/00;A61P35/00;C07D253/06;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D403/14;C07D405/04;C07D405/12;C07D405/14;C07D409/04;C07D409/12;C07D413/12;C07D413/14;C07D417/04;C07D453/02;C07D471/04;C07D471/08;C07D498/08;C07D498/10 |
主分类号 |
A61K31/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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