METHODS AND COMPOSITIONS FOR TREATING CANCER

摘要

The present disclosure relates to methods for treating a tumor or cancer by administering to a subject a PTEN inhibitor and a chemotherapeutic agent. The subject may be pre-treated with a vaccine that targets or comprises a tumor or cancer antigen or another therapeutic that enhances immune responses. The disclosure also provides compositions related to coadministration of a PTEN inhibitor, a chemotherapeutic and, optionally, a vaccine.