| 发明名称 |
TAT-INDUCED CRISPR/ENDONUCLEASE-BASED GENE EDITING |
| 摘要 |
Compositions and methods are provided for Tat-inducible expression of a CRISPR-associated endonuclease by a truncated HIV LTR promoter containing at least a core region and a TAR region of a HIV LTR promoter. The compositions may be used as a therapeutic treatment for the treatment and/or prevention of HIV. |
| 申请公布号 |
WO2016154016(A3) |
申请公布日期 |
2017.01.05 |
| 申请号 |
WO2016US23170 |
申请日期 |
2016.03.18 |
| 申请人 |
TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
KHALILI, Kamel |
| 分类号 |
A61P31/12;A61P31/18;C12N9/22;C12N15/49;C12N15/63 |
主分类号 |
A61P31/12 |
| 代理机构 |
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