发明名称 |
BISPECIFIC ANTIBODIES FOR USE IN CANCER IMMUNOTHERAPY |
摘要 |
The present invention concerns the field of cancer immunotherapy, and in particular drugs with low toxicity which can overcome drug-resistance. The present invention concerns novel bispecific antibodies which have the capability of binding both the TRAIL tumor associated antigen and the T lymphocyte CD3. The invention further relates to compositions comprising the bispecific antibodies and a labelling agent, and to pharmaceutical compositions. The present invention also relates to the use of the bispecific antibodies in the treatment of a tumor. |
申请公布号 |
WO2017001681(A1) |
申请公布日期 |
2017.01.05 |
申请号 |
WO2016EP65577 |
申请日期 |
2016.07.01 |
申请人 |
FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI |
发明人 |
FIGINI, Mariangela;SATTA, Alessandro;GIANNI, Alessandro Massimo;DI NICOLA, Massimo |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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