| 发明名称 |
METHOD FOR INVESTIGATING A SAMPLE USING CARS MICROSCOPY |
| 摘要 |
A method for investigating a sample (1), derived from a biological source, using CARS microscopy is proposed, in which method a resonance signal generated by coherent anti-Stokes Raman scattering by excitation of at least one resonance site (5) of the sample (1) by means of laser irradiation is sensed in image-producing fashion. The method according to the present invention encompasses furnishing at least one resonance site (5) by means of a bioorthogonal reaction of an intrinsic chemical structure (2) of the sample (1) with at least one reaction partner (3, 6). |
| 申请公布号 |
US2017003225(A1) |
申请公布日期 |
2017.01.05 |
| 申请号 |
US201415039883 |
申请日期 |
2014.11.28 |
| 申请人 |
LEICA MICROSYSTEMS CMS GMBH |
发明人 |
SÄGMÜLLER Bernd |
| 分类号 |
G01N21/65 |
主分类号 |
G01N21/65 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for investigating a sample, derived from a biological source, using CARS microscopy, in which method a resonance signal generated by coherent anti-Stokes Raman scattering by excitation of at least one resonance site of the sample by means of laser irradiation is sensed in image-producing fashion,
wherein the method comprises furnishing at least one resonance site by means of a bioorthogonal reaction of an intrinsic chemical structure of the sample with at least one reaction partner. |
| 地址 |
Wetzlar DE |
