发明名称 CRYSTALLINE FORMS OF TYROSINE KINASE INHIBITORS AND THEIR SALTS
摘要 The invention relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzate, including the polymorphic form A, mixtures of the polymorphs, process for the preparation thereof and the use thereof in a pharmaceutical composition containing thereof.
申请公布号 US2017001969(A9) 申请公布日期 2017.01.05
申请号 US201414772264 申请日期 2014.03.14
申请人 Purdue Pharma L.P. 发明人 Wu Jay Jie-Qiang;Wang Ling
分类号 C07D261/20;A61K31/496 主分类号 C07D261/20
代理机构 代理人
主权项 1. A compound of Compound I, sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzate, with the following structure:
地址 Stamford CT US