发明名称 |
EMBIGIN INHIBITION FOR PROMOTION OF HEMATOPOIETIC STEM AND PROGENITOR CELL EXPANSION |
摘要 |
Disclosed herein are methods for enhancing hematopoietic reconstitution of a subject. One method involves administering a therapeutically effective amount of an inhibitor of Embigin to a recipient subject and can also optionally include administering hematopoietic stem/progenitor cells to the subject. Another method involves administering an inhibitor of Embigin to a donor prior to harvest of hematopoietic stem/progenitor cells. Pharmaceutical compositions relating to the methods are also described. |
申请公布号 |
WO2017004127(A1) |
申请公布日期 |
2017.01.05 |
申请号 |
WO2016US39969 |
申请日期 |
2016.06.29 |
申请人 |
THE GENERAL HOSPITAL CORPORATION;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
SCADDEN, David T.;SILBERSTEIN, Lev;KHARCHENKO, Peter |
分类号 |
A61K35/14;A61K35/28;A61K35/44;A61K35/50;A61K38/17;A61K39/00;A61K39/395;A61P7/00 |
主分类号 |
A61K35/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|