| 发明名称 |
DETECTING PODOCYTE INJURY IN DIABETIC NEPHROPATHY AND GLOMERULONEPHRITIS |
| 摘要 |
This document provides methods and materials involved in determining whether or not a mammal with diabetic nephropathy or glomerulonephritis is undergoing podocyte injury. For example, methods and materials related to the use of urinary microvesicles to determine whether or not a mammal with diabetic nephropathy or glomerulonephritis is undergoing podocyte injury are provided. |
| 申请公布号 |
US2017003299(A1) |
申请公布日期 |
2017.01.05 |
| 申请号 |
US201415100136 |
申请日期 |
2014.11.05 |
| 申请人 |
Mayo Foundation for Medical Education and Research |
发明人 |
Garovic Vesna D.;Jayachandran Muthuvel |
| 分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A flow cytometry method or enzyme-linked immunosorbent assay method for detecting diabetic nephropathy or glomerulonephritis, wherein said method comprises:
(a) performing flow cytometry or an enzyme-linked immunosorbent assay using a urine sample obtained from a mammal to detect the presence of an elevated level of urinary microvesicles expressing a podocyte, parietal, mesangial, or endothelial cell marker, and (b) classifying said mammal as having diabetic nephropathy or glomerulonephritis. |
| 地址 |
Rochester MN US |
