PROTEIN AND LIPID BIOMARKERS PROVIDING CONSISTENT IMPROVEMENT TO THE PREDICTION OF TYPE 2 DIABETES

摘要

The invention relates to biomarkers associated with Diabetes, including protein and lipid metabolite biomarkers, methods of using the biomarkers to determine the risk that an individual will develop Diabetes, and methods of screening a population to identify persons at risk for developing Diabetes and other pre-diabetic conditions.

主权项

1: A method of evaluating risk for developing a diabetic condition, the method comprising:
(a) obtaining biomarker measurement data for an individual, wherein the biomarker measurement data is representative of measurements of biomarkers in at least one biological sample from the individual; wherein said biomarkers comprise: (i) glucose, (ii) at least three protein biomarkers selected from the protein biomarkers in Table 1 and (iii) at least one lipid metabolite selected from the lipid metabolites in Table 2; and (b) evaluating risk for the individual developing a diabetic condition based on an output from a model, wherein the model is executed based on an input of the biomarker measurement data.