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1. A compound or a salt or solvate thereof having a Formula I: wherein: R1 is hydrogen; a C1-C6 alkyl group; a C2-C6 alkenyl group; a C2-C6 alkynyl group; a saturated or unsaturated homocycle or heterocycle comprising one 5- or 6-membered ring, a saturated or unsaturated homocycle or heterocycle comprising two fused 5- or 6-membered rings, or an alkylthiophene; and R1 optionally is substituted at one or more positions with a C1-C6 alkyl group, a C1-C6 alkoxy group, a halo group, a haloalkyl group, phenyl group which optionally is substituted with halo, a benzyl group which optionally is substituted with halo, a triazole group optionally substituted with a carboxyl group, a 2,5-dioxopyrrolidinyl-1-yl-carboxylate group, an amino group, an alkyl-N,N-dialkyl amino group, an alkyl-alkyoxy-amino group, an alkyl-alkyoxy-alkoxy-amino group, an alkyl-alkyoxy-alkoxy-carboxamide-alkyl-morpholine group, an alkyl-alkyoxy-alkoxy-carboxamide-alkyl-1-alkylpyrrolidine group, an alkyl-alkyoxy-alkoxy-carboxamide-alkyl-cyclohexyl group, or an alkyl-alkyoxy-alkoxy-carboxamide-alkyl-cyclobutyl group; an imidazole group; a pyridyl group optionally substituted with phenoxy; a pyrrolidinyl group, a piperazinyl group, a 4-alkylpiperazine group, a 4-benzylpiperazine group, an alkyl-4-alkylpiperazine group; a piperidinyl group; a 4-alkylpiperidine group; a 4-N,N,diakylaminopiperidine group; a morpholinyl group; an alkylmorpholine group; an amino group; an alkylamino group; a dialkyl amino group; an alkyl-N,N-dialkylamino group; an azide group; a hydroxyl group; an alkylhydroxyl group; an alkynylphenyl group; a phenylmethanone group; an oxyphenyl group; an oxycarboxyl group, or R1 has a formula selected from:and R3 has a formula selected fromand R4 is H, C1-C8 alkyl, phenyl, or succinimidyl; and
R2 is C1-C6 alkyl or pyridinyl (e.g., 2-yl, 3-yl, or 4-yl). |
