发明名称 |
AZASPIRO DERIVATIVES AS TRPM8 ANTAGONISTS |
摘要 |
The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor.; |
申请公布号 |
US2017002016(A1) |
申请公布日期 |
2017.01.05 |
申请号 |
US201515125615 |
申请日期 |
2015.03.16 |
申请人 |
RaQualia Pharma Inc. |
发明人 |
SHISHIDO Yuji;OHMI Masashi;ANDO Kazuo |
分类号 |
C07D491/056;A61K31/422;A61K31/423;C07D413/06;C07D403/06;A61K31/4184;C07D403/14;A61K31/497;C07D401/14;A61K31/4439;C07D417/14;A61K31/427;A61K31/4725;A61K31/4709;A61K31/4545;C07D417/06;C07D235/02;C07D403/10;C07D471/04;C07D401/12;C07D403/12;A61K31/506;A61K31/501;A61K31/444;A61K31/517;A61K31/502;A61K31/437;A61K31/519;C07D487/04;C07D409/10;A61K31/498;C07D491/048;A61K31/4355;A61K31/4985;A61K31/5025;C07D413/10;C07D263/52;C07D405/14;A61K31/538;C07D413/14 |
主分类号 |
C07D491/056 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Aichi JP |