发明名称 |
Method for preparing microparticles with reduced initial burst and microparticles prepared thereby |
摘要 |
The present invention relates to a method for preparing polymer microparticles with a reduced initial burst, and the polymer microparticles prepared thereby. More particularly, the present invention relates to a method for preparing drug-loaded polymer microparticles with a reduced initial burst comprising the step of contacting the polymer microparticles with an alcohol aqueous solution, the polymer microparticles prepared thereby, and use for drug delivery of the polymer microparticles. Accordingly, the present invention provides a novel method of preparing polymer microparticles with a reduced initial burst. The method of the present invention may be useful for preparing a new formulation of drug that can prevent various side effects caused by excessive release of drug. |
申请公布号 |
AU2012259657(B2) |
申请公布日期 |
2017.01.05 |
申请号 |
AU20120259657 |
申请日期 |
2012.05.21 |
申请人 |
SK Chemicals Co., Ltd. |
发明人 |
Kim, Hong Kee;Lee, Kyu Ho;Oh, Joon-Gyo;Lee, Bong-Yong |
分类号 |
A61K9/16;A61K9/14;A61K47/30 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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