Embodiments for loading and expanding particular cell types are described. Embodiments may include the use of hollow fiber membranes with particular characteristic such as hollow fibers with inner diameters that provide mechanical stimulus (e.g., radius of curvature greater than a dimension of a cell). In addition, embodiments may provide for manipulation of flow rates and other features that also provide mechanical stimuli and promote or enhance the growth of particular types of cells.
申请公布号
WO2017004592(A1)
申请公布日期
2017.01.05
申请号
WO2016US40855
申请日期
2016.07.01
申请人
TERUMO BCT, INC.
发明人
JONES, Mark, E.;NANKERVIS, Brian, J.;FUERST, Kristina, E.;DODD, Jon, A.