发明名称 |
CYCLE ADENOSINE MONOPHOSPHATE-INCOMPETENT ADENYLYL CYCLASE AND COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE AND INCREASING CARDIAC FUNCTION |
摘要 |
The invention provides methods for treating, ameliorating or protecting (preventing) an individual or a patient having or at risk of having heart disease or heart failure, or decreased cardiac function, comprising: providing a cyclic adenosine monophosphate-incompetent (cAMP-incompetent) adenylyl cyclase type 6 (AC6) protein or polypeptide (also called “an AC6mut”), or an AC6mut-encoding nucleic acid or a gene operatively linked to a transcriptional regulatory sequence. |
申请公布号 |
EP3004343(A4) |
申请公布日期 |
2017.01.04 |
申请号 |
EP20140808138 |
申请日期 |
2014.06.04 |
申请人 |
The Regents of the University of California |
发明人 |
HAMMOND, H., Kirk;GAO, Mei, Hua |
分类号 |
C12N9/88;A61K38/51 |
主分类号 |
C12N9/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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