| 摘要 |
The present invention provides a compound of formula (I), wherein R 1 , R 2 , R 3 , R 4a , R 4b , R 5a and R 5b are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or treatment of a disease involving autotaxin, which is characterized by administering the compound. |
| 申请人 |
The University of Tokyo;Tohoku University;Shionogi & Co., Ltd. |
发明人 |
NAGANO, Tetsuo;OKABE, Takayoshi;KOJIMA, Hirotatsu;KAWAGUCHI, Mitsuyasu;NUREKI, Osamu;ISHITANI, Ryuichiro;NISHIMASU, Hiroshi;AOKI, Junken;FUJIKOSHI, Chiaki;KATOU, Manabu;ODAN, Masahide;TANAKA, Nobuyuki;TATENO, Yusuke;YAMANE, Junji |
