发明名称 |
NUCLEAR MEDICINE DIAGNOSTIC IMAGING AGENT |
摘要 |
Provided is a radioactive labeled compound that can detect a secondary mutation of an epidermal growth factor receptor and which is a compound represented by Formula (1) described below or a pharmaceutically acceptable salt thereof. In Formula (1), L 1 is an alkanediyl group having 1 to 5 carbon atoms or an alkenediyl carbonyl group having 3 to 8 carbon atoms, R 1 is a radioactive halogen atom, or 5- to 7-membered monocyclic nitrogen-containing heterocycloalkyl that may have one substituent, R 2 is a 6- to 8-membered aryl group or nitrogen-containing heteroaryl group with one substituent, R 1 or R 2 contains a radioactive halogen atom or a radioactive carbon atom ( 11 C), and Y is -NH- or -O-. |
申请公布号 |
EP3112365(A1) |
申请公布日期 |
2017.01.04 |
申请号 |
EP20160167782 |
申请日期 |
2016.04.29 |
申请人 |
KYOTO UNIVERSITY;ARKRAY, Inc. |
发明人 |
SAJI, Hideo;KIMURA, Hiroyuki;MATSUDA, Hirokazu;NAKANISHI, Shuichi |
分类号 |
C07D471/04;A61K51/04;C07B59/00 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|