发明名称 |
ANTI-CXCR1 COMPOSITIONS AND METHODS |
摘要 |
The present invention provides methods of treating cancer by administering an IL8-CXCR1 pathway inhibitor (e.g., an anti-CXCR1 antibody or Repertaxin) alone or in combination with an additional chemotherapeutic agent such that non-tumorigenic and tumorigenic cancer cells in a subject are killed. The present invention also provides compositions and methods for detecting the presence of and isolating solid tumor stem cells in a patient (e.g., based on the presence of CXCR1 or FBXO21). |
申请公布号 |
EP2356462(B1) |
申请公布日期 |
2017.01.04 |
申请号 |
EP20090826676 |
申请日期 |
2009.11.11 |
申请人 |
The Regents of the University of Michigan |
发明人 |
WICHA, Max S.;GINESTIER, Christophe |
分类号 |
G01N33/574 |
主分类号 |
G01N33/574 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|