The invention relates to polypeptide fragments of sclerostin and antibodies that bind to the fragments. The antibodies are useful in treating diseases of low bone density, such as osteoporosis, and in accelerating the healing of bone fractures.
申请公布号
EP2251351(B1)
申请公布日期
2017.01.04
申请号
EP20100006930
申请日期
2006.04.28
申请人
Amgen Inc.
发明人
Lu, Hsieng Sen;Paszty, Christopher;Robinson, Martyn Kim;Henry, Alistair James;Hoffmann, Kelly Sue;Latham, John;Lawson, Alastair;Winkler, David;Winters, Aaron George
