发明名称 |
SPECIFIC ACTIVATION OF A REGULATORY T CELL AND ITS USE FOR TREATMENT OF ASTHMA, ALLERGIC DISEASE, AUTOIMMUNE DISEASE, GRAFT REJECTION AND FOR TOLERANCE INDUCTION |
摘要 |
The present invention relates to a Treg cell activator for regulatory (Treg) cell activation via interaction with a Treg cell epitope as set forth in SEQ ID NO:1 which is HIV-1 gp120, or HIV-1 gp120 derived fragments, peptides or polypeptides thereof comprising an amino acid sequence as set forth in SEQ ID NO.: 3, SEQ ID NO.: 4, SEQ ID NO.: 5, SEQ ID NO.: 6, SEQ ID NO.: 7, SEQ ID NO.: 8, SEQ ID NO.: 9, or SEQ ID NO.: 10
for use in a method for the prevention or treatment of a disease, which is characterized in that its clinical picture is influenced positively by an increase of activated Treg cells in response to the Treg cell activator. |
申请公布号 |
EP3112866(A1) |
申请公布日期 |
2017.01.04 |
申请号 |
EP20160166807 |
申请日期 |
2008.01.30 |
申请人 |
Universitätsmedizin der Johannes Gutenberg-Universität Mainz |
发明人 |
SCHNEIDER, Franz-Josef;BECKER, Christian;BOPP, Tobias;JONULEIT, Helmut;SCHMITT, Edgar |
分类号 |
G01N33/50;A61K38/16;C07K14/00;C07K16/18 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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