发明名称 |
NOVEL POLYSACCHARIDE AND USES THEREOF |
摘要 |
Provided herein is a novel E. coli O polysaccharide, O25B. Also provided herein are prokaryotic host cells comprising enzymes (e.g., glycosyltransferases) used in O25B production. The host cells provided herein produce O25B bioconjugates, wherein said bioconjugates comprise O25B linked to a carrier protein. Further provided herein are compositions, e.g., pharmaceutical compositions, comprising O25B and/or bioconjugates comprising O25B. Such compositions can be used as vaccines against infection with ExPEC, and may further comprise one or more additional bioconjugates. |
申请公布号 |
EP3110441(A1) |
申请公布日期 |
2017.01.04 |
申请号 |
EP20150706459 |
申请日期 |
2015.02.23 |
申请人 |
Glycovaxyn AG |
发明人 |
KOWARIK, Michael, T.;WETTER, Michael, L.;KEMMLER, Stefan, J.;HÄUPTLE, Micha, A.;GAMBILLARA, Veronica;MALLY, Manuela |
分类号 |
A61K39/02;C07K14/24 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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