发明名称 Antiviral agent against animal viruses
摘要 Provided is an antiviral agent against animal viruses. The antiviral agent contains a protein or a nucleic acid sequence encoding the protein, as an active ingredient, the protein having binding ability and degrading ability to foreign nucleic acid chains invaded in an animal cell and that has no cytotoxicity to the animal cell itself. Also provided is an antiviral animal cell containing the protein according to the present invention, or the nucleic acid sequence encoding the protein. The antiviral agent and antiviral animal cell exhibit advantageous effects in that they selectively degrade foreign nucleic acid chains invaded in an animal cell and have no cytotoxicity to the animal cell, thus causing no death of the animal cell.
申请公布号 US9534040(B2) 申请公布日期 2017.01.03
申请号 US201414453149 申请日期 2014.08.06
申请人 Sungkyunkwan University Foundation for Corporate Collaboration;Ajou University Industry-Academic Cooperation Foundation;Invitroplant Co., Ltd.;Ministry of Agriculture Food and Rural Affairs Animal and Plant Quarantine Agency 发明人 Lee Suk-Chan;Kim Yong-Sung;Kwon Myung-Hee;Kim Tai-Hyun;Kim Jeong-Sun;Lee Gun-Sup;Shim Hye-Kyung;Park Eul-Yong;Chung Yu-Chul;Kim Ki-Yoon;Jung Yi-Jung;Lee Woo-Ram;Kim Young-Rim;Sohn Jong-Nam;Lee Seung-Hyun;Song Jae Young;Choi Eun Jin
分类号 C07K16/10;C07K16/44;C07K14/47;A61K39/00;A61K39/395 主分类号 C07K16/10
代理机构 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. 代理人 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Kim Kongsik
主权项 1. A method of inhibiting an RNA virus comprising contacting said RNA virus with a composition comprising a single-chain variable fragment (scFv) consisting of the sequence set forth in SEQ ID NO: 6, wherein said composition degrades RNA of said RNA virus thereby inhibiting said RNA virus.
地址 Suwon, Gyeonggi-do KR