| 发明名称 |
European PRRSV strain |
| 摘要 |
The present invention is related to improved modified live PRRS vaccines containing new PRRSV European strains of PRRSV and methods of use and manufacture of such vaccines. |
| 申请公布号 |
US9534207(B2) |
申请公布日期 |
2017.01.03 |
| 申请号 |
US201414281287 |
申请日期 |
2014.05.19 |
| 申请人 |
Boehringer Ingelheim Vetmedica GmbH |
发明人 |
Burgard Kim;Kroll Jeremy;Layton Sarah M.;Ohlinger Volker;Orveillon Francois-Xavier;Pesch Stefan;Piontkowski Michael Dennis;Roof Michael B.;Utley Philip;Vaughn Eric Martin |
| 分类号 |
A61K39/225;C12N7/00;A61K39/12;A61K38/00;A61K39/00 |
主分类号 |
A61K39/225 |
| 代理机构 |
|
代理人 |
Morris Michael P.;Morrison Joyce L. |
| 主权项 |
1. A method of immunizing swine against porcine reproductive and respiratory syndrome (PRRS), said method comprising the step of administering to swine a vaccine composition including a live porcine reproductive and respiratory syndrome virus mixed with a pharmacologically compatible carrier agent, said virus comprising PRRS 94881 virus passaged at least 36 times in cell culture to modify the virus such that when the modified virus is administered to a swine or other mammal prone to PRRS, it fails to cause clinical signs of PRRS disease but is capable of inducing an immune response that immunizes the mammal against pathogenic forms of PRRS. |
| 地址 |
Ingelheim am Rhein DE |
