发明名称 |
QUINAZOLINE INHIBITORS OF ACTIVATING MUTANT FORMS OF EPIDERMAL GROWTH FACTOR RECEPTOR |
摘要 |
The invention relates to compounds of formula(I), or a pharmaceutically acceptable sait thereof: Formula (1) which possess inhibitory activity against activating mutant forms of EGFR,and are accordingly useful for their anti-cancer activity and in methods of treatment of the human or animal body. The invention also relates pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti- cancer effect in a warm-blooded animal such as man. |
申请公布号 |
TN2015000368(A1) |
申请公布日期 |
2017.01.03 |
申请号 |
TN20150000368 |
申请日期 |
2015.08.28 |
申请人 |
ASTRAZENECA AB |
发明人 |
LI, David, Yunzhi;WANG, Jiabing;YANG, Zhenfan;ZENG, Qingbei;ZHANG, Xiaolin |
分类号 |
A61K31/495;A61K31/505;C07D403/12 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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