Acellular dermal graft

摘要

An acellular dermal graft is provided. The acellular dermal graft may be useful in minimizing side effects caused after transplantation since an environment favorable for formation of new blood vessels and proliferation of autologous tissues is provided by forming a multi-penetration structure in an acellular dermal tissue, removing a basement membrane layer and/or subjecting corners to slope cutting, and transplantation is stably performed within a short transplantation time due to improved extensibility and flexibility of tissues. The acellular dermal graft may be useful in reducing a time required to recover tissues after transplantation since the transplantation is stably performed due to improved grafting reaction with a host tissue by enhancing uptake of fibroblasts and promoting angiogenic activities. Also, the acellular dermal graft may be useful in maintaining smooth external appearance since hypodermic implantation is easily performed upon transplantation, and the skin at a graft site does not protrude after transplantation.

主权项

1. An acellular dermal graft having multi directional multi-penetrations formed therein,
wherein the multi directional multi-penetrations have a multi-penetration structure along a vertical axis, and a horizontal-axis multi-penetration structure in which layers are alternately stacked so that transversally aligned penetrations are formed in one layer and longitudinally aligned penetrations are formed in another layer.