MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS

摘要

The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L 1 and PD-Ll/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.