BIOERODIBLE SILICON-BASED DELIVERY VEHICLES FOR DELIVERY OF THERAPEUTIC AGENTS

摘要

This invention discloses bioerodible delivery compositions for delivering peptide therapeutic agents. The delivery compositions comprise a porous silicon-based carrier material loaded with the therapeutic agent. The delivery compositions may be used in vitro or in vivo to deliver the therapeutic agent, preferably in a controlled fashion over an intended period of time such as over multiple days, weeks or months. The delivery compositions may be used for treating or preventing conditions of a patient such as chronic diseases.

主权项

1. A sustained release drug delivery composition comprising:
a porous carrier material comprising a silicon-based compound; and at least one therapeutic agent associated with the carrier material, wherein the at least one therapeutic agent includes adrenocorticotropic hormone (ACTH) or an analog thereof.