发明名称 BICYCLIC PYRIMIDINE COMPOUNDS
摘要 The present invention provides compounds of the Formula Iwherein X is a bond or CH; R is selected from the group consisting ofRand Rare each independently selected from the group consisting of CH and N; Ris H or CH; Ris H or CH; L is selected from the group consisting of -O(CH)-, -C(O)NH(CH)-, -CHC(O)NH(CH)-, -(CH)N(C(O)CH)CH-, -(CH)N(C(O)CH)CH-, -(CH)NH-, (CH)OCH-, -(CH)-, -(CH)NHCH-, -(CH)O-, and -CHO(CH)-; or pharmaceutically acceptable salts thereof. Compounds of this invention are autotaxin inhibitors.
申请公布号 EA025106(B1) 申请公布日期 2016.11.30
申请号 EA20150091098 申请日期 2014.01.07
申请人 ELI LILLY AND COMPANY 发明人 BEAUCHAMP Thomas, James;DAO Yen;JONES Spencer, Brian;NORMAN Bryan, Hurst;PFEIFER Lance, Allen
分类号 C07D487/04;A61K31/5025;A61P29/00;C07D471/04 主分类号 C07D487/04
代理机构 代理人
主权项
地址