摘要 |
The present invention provides compounds of the Formula Iwherein X is a bond or CH; R is selected from the group consisting ofRand Rare each independently selected from the group consisting of CH and N; Ris H or CH; Ris H or CH; L is selected from the group consisting of -O(CH)-, -C(O)NH(CH)-, -CHC(O)NH(CH)-, -(CH)N(C(O)CH)CH-, -(CH)N(C(O)CH)CH-, -(CH)NH-, (CH)OCH-, -(CH)-, -(CH)NHCH-, -(CH)O-, and -CHO(CH)-; or pharmaceutically acceptable salts thereof. Compounds of this invention are autotaxin inhibitors. |