JOINT PRODUCT CONTAINING PHENTERMINE AND TOPIRAMATE AND PREPARATION METHOD THEREFOR
摘要
The present invention provides a combination product, which comprises immediate release pellet of phentermine and sustained-release pellet of topiramate, wherein the pellet of topiramate includes: a) a blank pellet core; b) an active drug layer that contains topiramate and is free of binding agent, the layer being located on surface of the blank pellet core; c) a sustained-release coating layer containing ethyl cellulose and PVP K30, the sustained-release coating layer being located on external of the active drug layer. The present invention further discloses a method for preparing the combination product.
申请公布号
EP2829266(B1)
申请公布日期
2016.11.30
申请号
EP20130763543
申请日期
2013.03.20
申请人
INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA