MICROFLUIDIC DEVICES WITH INTEGRATED RESISTIVE HEATER ELECTRODES INCLUDING SYSTEMS AND METHODS FOR CONTROLLING AND MEASURING THE TEMPERATURES OF SUCH HEATER ELECTRODES

摘要

The invention relates to methods and devices for control of an integrated thin-film device with a plurality of microfluidic channels. In one embodiment, a microfluidic device is provided that includes a microfluidic chip having a plurality of microfluidic channels and a plurality of multiplexed heater electrodes, wherein the heater electrodes are part of a multiplex circuit including a common lead connecting the heater electrodes to a power supply, each of the heater electrodes being associated with one of the microfluidic channels. The microfluidic device also includes a control system configured to regulate power applied to each heater electrode by varying a duty cycle, the control system being further configured to determine the temperature of each heater electrode by determining the resistance of each heater electrode.

主权项

1. A method for determining the resistance of a sensor in a multiplexed sensor network including a plurality of sensors sharing a common lead for connecting each of the plurality of sensors to a power supply, comprising:
sequentially measuring the combined series resistances for N number of distinct sensor pairs, such that each of the plurality of sensors is included in at least one of the measured sensor pairs, wherein N is the number of sensors in the plurality of sensors, and the measured sensor pairings are such that the individual resistance of each of the plurality of sensors may be determined; and determining for the individual resistance of at least one of the plurality of sensors based upon the measured combined series resistances.