发明名称 |
IN VITRO CELL CULTURE METHODS FOR BETA-THALASSEMIA USING ACTIVIN TYPE II RECEPTOR LIGAND TRAPS |
摘要 |
Provided herein are methods of treating beta-thalassemia in a subject comprising administering to the subject an activin type II receptor (ActRII) signaling inhibitor (e.g., an activin ligand trap) and utilizing one or more in vitro cell culture methods provided herein in (i) selection of the subject to be treated according to the methods provided herein; and/or (ii) monitoring of the subject being treated according to the methods provided herein. |
申请公布号 |
WO2016187378(A1) |
申请公布日期 |
2016.11.24 |
申请号 |
WO2016US33187 |
申请日期 |
2016.05.19 |
申请人 |
CELGENE CORPORATION;CAPPELLINI, Maria |
发明人 |
CAPPELLINI, Maria;SUNG, Victoria |
分类号 |
C07K14/705;C07K14/495;C07K14/52;C07K14/535;C07K14/545;C07K14/71;C12N1/00;C12N5/077 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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