METHOD OF PERFORMING A PLURALITY OF SYNTHESIS PROCESSES OF PREPARING A RADIOPHARMACEUTICAL IN SERIES, A DEVICE AND CASSETTE FOR PERFORMING THIS METHOD

摘要

The invention relates to a method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series, which method comprises carrying out a first synthesis run comprising the steps of: a) providing water containing 18F; b) trapping the 18F from the water provided in step a) on an anion exchange material (18); c) eluting the trapped 18F from the anion exchange material (18) to a reaction vessel (58) of first radiopharmaceutical synthesis cassette (50'); d) preparing a radiopharmaceutical incorporating the eluted 18F using the first radiopharmaceutical synthesis cassette (50'); wherein steps a)-d) are repeated in at least one subsequent run using another radiopharmaceutical synthesis cassette (50"; 50"'); and wherein the method comprises a reconditioning step of said anion exchange material (18) between two consecutive runs Other aspects of the invention relate to a device for performing this method, and a cassette for use in the device.