发明名称 |
A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION |
摘要 |
The present invention relates to compositions and methods for modulating melanin production, secretion and/or accumulation in human skin cells. In particular, the present invention relates to the use of A3 adenosine receptor antagonists in compositions and methods for the treatment and amelioration of hyper-pigmentation conditions and for the lightening of skin, and to the use of A3 adenosine receptor agonists in compositions and methods for the treatment and amelioration of hypo-pigmentation conditions and for the tanning of skin. |
申请公布号 |
EP2456419(B1) |
申请公布日期 |
2016.11.23 |
申请号 |
EP20100750183 |
申请日期 |
2010.07.20 |
申请人 |
ORADIN PHARMACEUTICAL LTD. |
发明人 |
MADI, LEA LEVANA;KORENSTEIN, RAFI |
分类号 |
A61K31/4418;A61K8/49;A61K8/60;A61K31/7076;A61P17/00;A61Q19/02;A61Q19/04 |
主分类号 |
A61K31/4418 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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