发明名称 IMMUNOGLOBULIN AGAINST THE ANTHRAX TOXIN
摘要 The present invention relates to a class-G immunoglobulin against the anthrax toxin protective antigen (PA), or one of the fragments of same, comprising at least: a variable heavy-chain region comprising an amino acid sequence represented by the sequence SEQ ID NO: 1, or comprising an amino acid sequence having at least 90% identity with the sequence SEQ ID NO: 1, and comprising the amino acids. Leucine in position 51 and Glycine in position 67, and a variable light-chain region comprising an amino acid sequence represented by the sequence SEQ ID NO: 2, or comprising an amino acid sequence having at least 90% identity with the sequence SEQ ID NO: 2, and comprising a Leucine amino acid in position 55. The invention also relates to the uses of such an immunoglobulin.
申请公布号 EP3094645(A1) 申请公布日期 2016.11.23
申请号 EP20150704054 申请日期 2015.01.16
申请人 LABORATOIRE FRANÇAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES;ETAT FRANÇAIS REPRÉSENTÉ PAR LE DIRECTEUR CENTRALDU SERVICE DE SANTÉ DES ARMÉES 发明人 BEHRENS, CHRISTIAN;KLEIN, PHILIPPE;HOGUET, DENIS
分类号 C07K16/12;A61K39/395;A61K39/40;A61K47/42;A61P31/04;C12N15/13;C12N15/63;G01N33/53;G01N33/569 主分类号 C07K16/12
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