发明名称 INDAZOLE COMPOUNDS AS IRAK4 INHIBITORS
摘要 The present invention provides indazole compounds of formula (I), which are therapeutically useful as kinase inhibitors, particularly IRAK4 inhibitors, wherein Z1, Z2, R1, R2, R3, ‘m’ and ‘n’ have the meanings given in the specification, and pharmaceutically acceptable salts or stereoisomers thereof that are useful in the treatment and prevention of diseases or disorders, in particular their use in diseases or disorders mediated by kinase enzyme, particularly IRAK4 enzyme. The present invention also provides pharmaceutical compositions comprising at least one of the compounds of the compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient.
申请公布号 EP3092226(A1) 申请公布日期 2016.11.16
申请号 EP20150703102 申请日期 2015.01.07
申请人 AURIGENE DISCOVERY TECHNOLOGIES LIMITED 发明人 GUMMADI, VENKATESHWAR RAO;SAMAJDAR, SUSANTA;GUPTA, AJAY
分类号 C07D401/14;A61K31/416;A61P27/02;A61P35/00;A61P37/00;C07D405/14;C07D413/14 主分类号 C07D401/14
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