PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES
摘要
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.
申请公布号
EP2686321(B1)
申请公布日期
2016.11.16
申请号
EP20120710852
申请日期
2012.03.16
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
WROBLESKI, STEPHEN T.;DAS, JAGABANDHU;DUAN, JINGWU;GUO, JUNQING;HYNES, JOHN;JIANG, BIN;KEMPSON, JAMES;LIN, SHUQUN;LU, ZHONGHUI;PITTS, WILLIAM J.;SPERGEL, STEVEN H.;WU, HONG;YANG, BINGWEI VERA