The present invention refers to methods for selectively recognizing a base pair in a DNA sequence by a polypeptide, to modified polypeptides which specifically recognize one or more base pairs in a DNA sequence and, to DNA which is modified so that it can be specifically recognized by a polypeptide and to uses of said polypeptide and DNA in specific DNA targeting as well as to methods of modulating expression of target genes in a cell.
申请公布号
EP2379583(B1)
申请公布日期
2016.11.09
申请号
EP20100706358
申请日期
2010.01.12
申请人
BONAS, ULLA;BOCH, JENS;SCHORNACK, SEBASTIAN;LAHAYE, THOMAS
发明人
BONAS, ULLA;BOCH, JENS;SCHORNACK, SEBASTIAN;LAHAYE, THOMAS