| 发明名称 |
COMBINATION THERAPY FOR TREATING CANCER |
| 摘要 |
The present invention relates to compositions comprising inhibitors of human histone methyltransferase DOT1L and one or more therapeutic agents, particularly anticancer agents, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer. |
| 申请公布号 |
EP2968343(A4) |
申请公布日期 |
2016.11.02 |
| 申请号 |
EP20140769036 |
申请日期 |
2014.03.14 |
| 申请人 |
EPIZYME, INC. |
发明人 |
KLAUS, CHRISTINE;RAIMONDI, MARIA ALEJANDRA;DAIGLE, SCOTT RICHARD;POLLOCK, ROY MACFARLANE |
| 分类号 |
A61K31/52;A61K31/136;A61K31/4745;A61K31/551;A61K31/704;A61K31/706;A61K31/7064;A61K31/7068;A61K31/7076;A61P35/00;C07D473/34;C07D487/04;C07H19/044;C07H19/16 |
主分类号 |
A61K31/52 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
