发明名称 |
METHOD FOR PREPARING HYDROXYPROPYL METHYLCELLULOSE ACETATE SUCCINATE (HPMCAS) GRAINS HAVING CONTROLLED GRAIN SIZE DISTRIBUTION, AND HPMCAS POWDER |
摘要 |
Disclosed are a method for preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains and HPMCAS grains. The disclosed method for preparing HPMCAS grains comprises: a step of esterifying hydroxypropyl methylcellulose (HPMC), acetic anhydride, and succinic anhydride in a reaction medium in the presence of a catalyst so as to obtain a reaction solution containing HPMCAS (esterification step); and a step of continuously or intermittently putting the reaction solution into water so as to form grains (granulating step). |
申请公布号 |
US2016311932(A1) |
申请公布日期 |
2016.10.27 |
申请号 |
US201415104561 |
申请日期 |
2014.12.15 |
申请人 |
LOTTE FINE CHEMICAL CO., LTD. |
发明人 |
BANG Sung Hwan;SHIN Ju Hee;SON Jin Ryul;PARK Kyung Yeol;CHUN Jeong Hee;JEONG Ji Seon;LEE Sang Youb |
分类号 |
C08B13/00 |
主分类号 |
C08B13/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method of preparing hydroxypropyl methylcellulose acetate succinate (HPMCAS) grains, the method comprising:
obtaining a reaction solution comprising HPMCAS by esterifying hydroxypropyl methylcellulose (HPMC), acetic anhydride, and succinic anhydride in a reaction medium in the presence of a catalyst (esterification step); and forming grains by continuously or intermittently adding the reaction solution to water (granulating step). |
地址 |
Ulsan KR |