发明名称 CARBOSTYRIL DERIVATIVES AND SEROTONIN REUPTAKE INHIBITORS FOR TREATMENT OF MOOD DISORDERS
摘要 The pharmaceutical composition of the present invention comprises (1) a carbostyril derivative and (2) a serotonin reuptake inhibitor in a pharmaceutically acceptable carrier. The carbostyril derivative may be aripiprazole or a metabolite thereof, which is a dopamine-serotonin system stabilizer. The serotonin reuptake inhibitor may be fluoxetine, duloxetine, venlafaxine, milnacipran, citalopram, fluvoxamine, paroxetine, sertraline or escitalopram. The pharmaceutical composition of the present invention is useful for treating patients with mood disorders, particularly depression or major depressive disorder.
申请公布号 US2016310489(A1) 申请公布日期 2016.10.27
申请号 US201615176464 申请日期 2016.06.08
申请人 Otsuka Pharmaceutical Co., Ltd. 发明人 Kikuchi Tetsuro;Iwamoto Taro;Hirose Tsuyoshi
分类号 A61K31/496;A61K31/138;A61K31/381;A61K31/135;A61K31/165;A61K31/15;A61K31/4525;A61K31/343;A61K31/137 主分类号 A61K31/496
代理机构 代理人
主权项
地址 Tokyo JP
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